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PDF] Pharmacokinetic/Pharmacodynamic (PK/PD) Indices of Antibiotics Predicted by a Semimechanistic PKPD Model: a Step toward Model-Based Dose Optimization | Semantic Scholar
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Erin McCreary on X: "@jpogue1 starts overview of polymyxins international consensus guideline with discussion on target to achieve 1 log kill. In murine thigh infection model, free AUC/MIC target ~12, total target ~
RESULTS INTRODUCTION CONCLUSIONS METHODS REFERENCES
![PDF] fAUC/MIC is the most predictive pharmacokinetic/pharmacodynamic index of colistin against Acinetobacter baumannii in murine thigh and lung infection models. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/d3d1393b02567dc69aadc62356613462423dca9b/3-Figure1-1.png "PDF] fAUC/MIC is the most predictive pharmacokinetic/pharmacodynamic index of colistin against Acinetobacter baumannii in murine thigh and lung infection models. | Semantic Scholar")