A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties
File:PegUricase.png - Wikipedia
Pegloticase immunogenicity: the relationship between efficacy and antibody development in patients treated for refractory chronic gout | Arthritis Research & Therapy | Full Text
In-silico epitope identification and design of Uricase mutein with reduced immunogenicity - ScienceDirect
Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase | Arthritis Research & Therapy
PEG Uricase: Long Acting Agent for Treating Gout | Biopharma PEG
Free PEGylation (uricase) Icons, Symbols & Images | BioRender
PEGylation: definition, principles, methods and benefits
Tolerogenic nanoparticles mitigate the formation of anti-drug antibodies against pegylated uricase in patients with hyperuricemia | Nature Communications
Effect of treatment with PEG-uricase on uric acid excretion. Ten... | Download Scientific Diagram
Pegloticase co-administered with high MW polyethylene glycol effectively reduces PEG-immunogenicity and restores prolonged circulation in mouse - ScienceDirect
PEG Uricase Long Acting Agent for Treating Gout
Enhancing the Response Rate to Recombinant Uricases in Patients with Gout | BioDrugs
PEG antibodies do not cross‐react with uricase‐POEGMA. The reactivity... | Download Scientific Diagram
Plasma uricase activity and plasma uric acid concentrat | Open-i
![PDF] Critical appraisal of the role of pegloticase in the management of gout | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/524af92aa8e23a0d80d9573d0e429459a3d69e04/2-Figure1-1.png "PDF] Critical appraisal of the role of pegloticase in the management of gout | Semantic Scholar")
PDF] Critical appraisal of the role of pegloticase in the management of gout | Semantic Scholar
Immunogenicity of unmodified uricase and PEG-uricases. The development... | Download Scientific Diagram
Anti-PEG Abs in the clinic 2 . 1 The case of PEG-uricase | Semantic Scholar
WO2003011211A2 - Peg-modified uricase - Google Patents
Effect of treatment with PEG-uricase on the development of diabetes... | Download Scientific Diagram
RT @Janetbirdope: Cool way to get peg uricase tolerated in #gout. ##Rapamycin nanoparticle Rx w SEL 212 a uricase -infus | RheumNow
Hyperuricemia and Gout: New Clinical Insights and Emerging Treatments
Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase | Arthritis Research & Therapy
Uricase Modified Au/Ni/PANI Microrockets to Reduce Uric Acid Level | Catalysis Letters
Zwitterionic Nanocages Overcome the Efficacy Loss of Biologic Drugs | UW Bioengineering
Zwitterionic Nanocages Overcome the Efficacy Loss of Biologic Drugs
